| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | Adapter molecule crk;Proto-oncogene c-Crk;p38;CRK; |
| Cellular Localization | |
| Clonality | |
| Concentration | |
| Host | |
| Immunogen | A synthesized peptide derived from human Phospho-PBK/TOPK (Thr9) |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Target | |
| UniProt # |
Boster Bio Anti-Phospho-PBK/TOPK (Thr9) Rabbit Monoclonal Antibody catalog # P02623. Tested in WB, IHC applications. This antibody reacts with Human.
Gene: Adapter molecule crk | Target: PBK | Function: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk- II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling. . | Research areas: Adapters,Cancer,Cytoplasmic,Signal Transduction
Host: Rabbit | Clonality/Clone: Monoclonal / Clone: 30P33 | Isotype: IgG | Reactivity: Human | Immunogen: A synthesized peptide derived from human Phospho-PBK/TOPK (Thr9) | Concentration: 0.5mg/ml | Purification: Affinity-chromatography
Applications: WB, IHC
Observed MW: 40 kDa | Calculated MW: 33831 MW
Cellular localization: Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .
Tissue details: Expressed in brain, and to a lesser extent in lung, kidney and testis.
Phospho site(s): Thr9
Status: Active
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
