Anti-SUMO2/3 Antibody Picoband®

Overview

Anti-SUMO2/3 Antibody Picoband® is an antibody for SUMO2/3 detection raised in Rabbit (Polyclonal, Rabbit IgG), with reported reactivity: Human,Mouse,Rat. Commonly used in WB, IHC, IF, ICC, Flow Cytometry, ELISA workflows.

Key elements and design rationale

• Target: SUMO2/3 (CD81 antigen); UniProt: P61956/P55854; NCBI Gene: 6613/6612
• Antibody format: Rabbit, Polyclonal, Rabbit IgG
• Molecular weight: 20 kDa
• Applications: WB, IHC, IF, ICC, Flow Cytometry, ELISA

Vendor description (summary): Boster Bio Anti-SUMO2/3 Antibody Picoband® catalog # A01282-2.

Biological background

Biological context: May play an important role in the regulation of lymphoma cell growth. May be involved in the acrosome reaction.

Expression and localization notes: cellular localization: Basolateral cell membrane., tissue context: Expressed in oocytes. Highly expressed in granulosa cells..

Common research applications

• Western blotting (WB): Compare SUMO2/3 levels across samples and conditions using appropriate loading and biological controls.
• Immunohistochemistry (IHC): Evaluate spatial distribution of SUMO2/3 in tissue sections, considering fixation and antigen retrieval effects.
• Immunofluorescence / ICC: Assess subcellular localization patterns and co-localization with compartment markers in cultured cells.
• Flow cytometry: Quantify SUMO2/3-positive populations in single-cell suspensions with appropriate gating and controls.
• ELISA: Use antibody-based detection formats to assess antigen presence or binding in plate-based assays.

Notes for experimental interpretation

• Account for isoforms, post-translational modifications, and sample-specific processing that can shift apparent molecular weight or epitope accessibility.
• Use positive/negative biological controls where possible (e.g., known-expressing cells/tissues, knockdown/knockout models) and include appropriate secondary-only/isotype controls for imaging workflows.

Additional product notes (from provided fields)

• Background: Small ubiquitin-related modifier 2,3 is a protein that in humans is encoded by the SUMO2,3 gene. This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
• Cross reactivity: No cross-reactivity with other proteins.
• Cellular localization: Basolateral cell membrane.
• Tissue details: Expressed in oocytes. Highly expressed in granulosa cells.
• Research category: Adaptive Immunity,B Cells,Host-Virus Interaction,Human Protein,Immunology,Interspecies Interaction,Microbiology,Protein

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.