| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Cas No. | |
| Form | Yellow powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (15 mg/ml); or ethanol (3 mg/ml) |
| Source | Synthetic |
| Storage |
Clozapine N-oxide (CNO) is a pharmacologically inert compound that selectively activates designer receptors exclusively activated by designer drugs (DREADDs). In neuroscience, CNO is widely used in chemogenetic studies to modulate neuronal activity with high spatial and temporal precision. It enables researchers to investigate neural circuits underlying behavior, cognition, and neurodegenerative processes by selectively activating or inhibiting specific neuronal populations.
GHS Classification: GHS06 Acute toxicity (oral, dermal, inhalation), categories 1,2,3 Hazard statement(s): H301-H336
Clozapine N-oxide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-570)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
