| Field | Specification |
|---|---|
| Alternative names | (3S,3aR,4S,6S,6aR,7E,10S,12S,13E,15R,15aR)-3-Benzyl-6-hydroxy-4,10,12-trimethyl-5-methylene-1-oxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate, Zygosporin A |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C30H37NO6 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble to 10 mM in ethanol and to 50 mM in DMSO |
| SMILES | |
| InChIKey | |
| Form | White Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Cytochalasin D binds to actin filaments and inhibits their polymerization and elongation, leading to changes in cellular morphology and apoptosis. In neuroscience, it is widely used to study cytoskeletal dynamics, synaptic plasticity, and neuronal migration. Its ability to disrupt actin networks makes it a powerful agent for probing the role of the cytoskeleton in neurodevelopment and neurodegeneration.
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Risk Phrases:
- R62 - Possible risk of impaired fertility
- R68 - Possible risk of irreversible effects
Hazard Phrases:
H300-H361
Precautionary Phrases:
P264-P281-P301 + P310
Cytochalasin D (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-241)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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2. Ornelles et al., (1986) Mol Cell Biol. 6(5): 1650-1662.
