| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | N,N'-Dibenzyl-2,4-quinazolinediamine, JRF 12, N2,N4-dibenzylquinazoline-2,4-diamine, N2,N4-Bis(phenylmethyl)-2,4-quinazolinediamine |
| Form | Yellow Powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in 25 mg/ml DMSO |
| Source | Synthetic |
| Storage |
DBeQ is a selective and reversible inhibitor of the AAA-ATPase p97, which is involved in ubiquitin-dependent protein clearance. It is cell permeable and used in neuroscience to study protein degradation pathways, ER stress responses, and neurodegenerative mechanisms linked to impaired proteostasis.
Classification: Toxic Material Causing other toxic effects- moderate eye irritant.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S24/25- Avoid contact with skin and eyes
Hazard Statements:
H302 – Harmful if swallowed
Precautionary Statements:
P305 + P351 + P338 – If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
DBeQ (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-334)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
