| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Pictrelisib, Pictilisib, GNE 0941, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)-thieno[3,2-d]pyrimidine |
| Cas No. | |
| Form | White solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO |
| Source | Synthetic |
| Storage |
GDC 0941 is a potent and selective inhibitor of class I phosphoinositide 3-kinases (PI3Ks), including PI3Kα, β, δ, and γ isoforms. While primarily investigated in oncology for its role in inhibiting tumor growth and survival pathways, PI3K signaling is also critical in neuronal function, synaptic plasticity, and neuroinflammation. GDC 0941’s modulation of PI3K pathways presents potential applications in neurodegenerative disease models, particularly those involving dysregulated cell survival and neuroimmune responses.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
GDC 0941 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-501)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
