| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Form | Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | In aqueous solution |
| Source | Synthetic |
| Storage |
The Hsp70 TKD peptide is a synthetic fragment derived from the heat shock protein 70 (Hsp70), specifically the amino acid sequence TKDNNLLGRFELSG. In neurodegenerative disease research, Hsp70 and its derivatives are of interest due to their roles in protein folding, stress response, and immune modulation. The TKD peptide has been shown to activate natural killer (NK) cells and enhance immune surveillance, which may be beneficial in clearing damaged or aggregated proteins in neurodegenerative conditions. Its immunomodulatory properties suggest potential for therapeutic strategies aimed at enhancing neuroimmune interactions.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Hsp70 TKD Peptide (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-118)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Rothman J. (1989), Cell 59: 591 -601.
3. DeLuca-Flaherty et al. (1990) Cell 62: 875-887.
4. Bork P., Sander C. & Valencia A. (1992) Proc. Natl Acad. Sci. USA 89:7290-7294.
5. Multhoff G., et al. (2001) Cell Stress Chaperones 6 (4): 337-344.
6. Krause, S. W. et al. (2004) Clin. Cancer Res. 10(11): 3699-3707.
