| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA was used as the immunogen for the was used as the immunogen for the IGF1R alpha antibody. The epitope has been localized to the alpha subunit, between amino acids 184 and 283. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
IGF1R alpha Antibody / Insulin like growth factor 1 receptor alpha is an antibody targeting IGF1R. Host: Mouse. Monoclonal. Clone: 24-60. Format: Purified. Applications: IF.
Key elements and design rationale
- Target: IGF1R.
- Immunogen: IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA was used as the immunogen for the was used….
- Species reactivity: Human.
- Localization: Cell membrane.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
This antibody is specific for the human insulin-like growth factor 1 receptor (IGF1R). It recognizes the extracellular portion of the receptor, specifically an epitope in the cysteine rich domain of the alpha subunit, between amino acids 184 and 283. It does not cross-react with rat or mouse IGF1R or human insulin receptors in co-precipitation or immuno-depletion assays.
Common research applications
- IF/ICC: subcellular localization imaging with proper background controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
