| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human IL22 was used as the immunogen for the IL22 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
IL22 Antibody / Interleukin 22 is a anti-IL22 Rabbit antibody Recombinant Rabbit Monoclonal clone 31I09 supplied in Liquid format. Recommended for workflows such as Western blot (WB) with listed reactivity in Human.
Key elements and design rationale
- Target: IL22
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 31I09, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB
Biological background
IL22 antibody is commonly used in immunology, infectious disease, and cancer research. By detecting IL22 expression, researchers can explore how cytokine networks regulate immune responses at mucosal surfaces and within tissues. IL22 is known to induce antimicrobial peptide production in epithelial cells, enhancing resistance to bacterial and fungal pathogens. It also contributes to tissue regeneration following injury, linking immunity with repair mechanisms.
The antibody is suitable for western blotting, immunohistochemistry, immunofluorescence, and flow cytometry. In flow cytometric assays, IL22 antibody enables quantitative analysis of cytokine production by T cells or innate lymphoid cells. Immunohistochemistry localizes IL22 expression within tissues, highlighting immune epithelial interactions. Immunofluorescence allows visualization of cytokine production at the cellular level, while western blotting confirms protein expression in experimental samples. These applications make IL22 antibody a versatile reagent for diverse research programs.
In disease contexts, IL22 has a dual role. It provides protective immunity in infections and promotes wound healing, but excessive or chronic IL22 signaling contributes to inflammatory diseases such as psoriasis, colitis, and arthritis. Monitoring IL22 with specific antibodies helps define its protective versus pathogenic roles. In oncology, IL22 has been implicated in promoting tumor growth by enhancing cell survival, angiogenesis, and invasion in certain cancers. These opposing effects underscore the importance of precise measurement using reliable reagents.
IL22 antibody is also valuable for therapeutic research. Neutralizing IL22 signaling may help treat autoimmune or inflammatory diseases, while enhancing IL22 activity could be beneficial for boosting host defense and tissue repair. Antibody based studies allow scientists to evaluate these strategies by accurately tracking IL22 levels in preclinical and translational models.
IL22 antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
