| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Interleukin-1 Receptor Antagonist antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
Interleukin-1 Receptor Antagonist Antibody / IL-1RA / IL-1RN is an antibody targeting Interleukin-1. Host: Mouse. Monoclonal. Clone: IL1RA/4715. Format: Purified. Applications: IHC-P.
Key elements and design rationale
- Target: Interleukin-1.
- Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for….
- Species reactivity: Human.
- Localization: Cytoplasm, Secreted.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
Two forms of interleukin-1, designated IL-1a and IL-1beta, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1a and IL-1beta bind to the same receptor and seem to elicit similar biological responses.
Common research applications
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
