| Field | Specification |
|---|---|
| Target | |
| Alternative names | Bispecific, Receptor tyrosine-protein kinase erbB-2, 2.7.10.1, Metastatic lymph node gene 19 protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340, ERBB2, HER2, MLN19, NEU, NGL, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Purity | |
| Purification | |
| Concentration | |
| Form | Liquid |
| Storage | |
| Storage buffer | |
| Catalog no. (Mfr.) | |
| Main SKU |
Overview
InVivoMAb Anti-Human ERBB2/HER-2 & CD3e Bispecific Antibody (Iv0231) targets ERBB2/HER-2 & CD3e Bispecific (Tyrosine kinase-type cell surface receptor HER2). Frequently used across FuncS workflows, depending on experimental design and sample type. This antibody is suited for workflows commonly used in Cell Signaling research.
Also known as: Tyrosine kinase-type cell surface receptor HER2, Receptor tyrosine-protein kinase erbB-2, T-cell surface glycoprotein CD3 epsilon chain, Metastatic lymph node gene 19 protein, T-cell surface antigen T3/Leu-4 epsilon chain, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, MLN 19.
Target biology
ERBB2/HER-2 & CD3e Bispecific (Tyrosine kinase-type cell surface receptor HER2) encodes a receptor kinase that converts extracellular cues into phosphorylation-driven signaling programs controlling growth, survival, or differentiation. Receptor processing and activation state can affect apparent banding and signal intensity across assays. Common alternative names and symbols used in the literature include: Receptor tyrosine-protein kinase erbB-2, T-cell surface glycoprotein CD3 epsilon chain, Metastatic lymph node gene 19 protein, T-cell surface antigen T3/Leu-4 epsilon chain, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, MLN 19. Based on the annotated name/class, the target is most often associated with plasma membrane and/or intracellular membranes localization, though this can vary by model system.
How this antibody helps
As a monoclonal reagent, this antibody is designed for clone-to-clone consistency and epitope-focused recognition. For best performance, interpret signal in the context of appropriate biological controls and orthogonal readouts when available.
Recommended experimental notes
- Titrate the antibody to optimize signal-to-noise for your specific sample type and detection system.
- Use appropriate positive and negative controls (e.g., target-high vs target-low samples, KO/KD where available).
Additional notes
For research use only. Not suitable for clinical or therapeutic use.
For research use only. Not for diagnostic procedures.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
