| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one; NSC-664704 |
| Cas No. | |
| Form | Beige powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (35 mg/ml) |
| Source | Synthetic |
| Storage |
Kenpaullone is a potent inhibitor of cyclin-dependent kinases (CDKs) such as CDK2 and CDK5, as well as casein kinase 1 (CK1) and glycogen synthase kinase 3 beta (GSK3β). These kinases are involved in cell cycle regulation, apoptosis, and tau phosphorylation. In neurodegenerative disease research, Kenpaullone is studied for its ability to inhibit aberrant kinase activity associated with Alzheimer’s disease and other tauopathies. By modulating key signaling pathways, Kenpaullone may help prevent neuronal death and protein aggregation, offering potential neuroprotective benefits.
Classification: Caution: Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Kenpaullone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-598)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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