LFM A13

SKU:BHB11900245
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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LFM A13 (2-Cyano-N-(2) is a research-grade small-molecule inhibitor of BTK kinase supporting Cell Signaling and Cancer research. Supplied as a yellow solid with 97% purity (CAS 62004-35-7, MW 360) soluble in DMSO or ethanol; store at -20°C. For research use only.
Cas No. 62004-35-7
Molecular Formula C11H8Br2N2O2
Purity ≥97% (TLC)
Application Notes BTK kinase inhibitor
Options selector
Catalog no. Size
SIH-461-5MG 5 mg
SIH-461-25MG 25 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 25 mg, 5 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-461
Activity
  • Inhibitor
Alternative Names 2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide
Cas No. 62004-35-7
Form Yellow solid
Molecular Weight 360
Product Type
  • Biochemicals
  • Small Molecules
Purity ≥97% (TLC)
Shipping Shipped Ambient
SMILES C/C(=C(\C#N)/C(=O)NC1=C(C=CC(=C1)Br)Br)/O
Solubility Soluble in DMSO (10 mg/ml) or ethanol (0.3 mg/ml)
Source Synthetic
Storage -20ºC

LFM A13 is a selective inhibitor of Bruton's tyrosine kinase (BTK), a key regulator of B-cell receptor signaling and innate immune responses. In neurodegenerative disease research, BTK has emerged as a target for modulating microglial activation and neuroinflammation. LFM A13 is used to explore the role of BTK in central nervous system immune responses and its potential as a therapeutic target in diseases such as multiple sclerosis and Alzheimer's disease.

Classification: Not a hazardous substance or mixture.

Safety Phrases:

  • S22 - Do not breathe dust.
  • S24/25 - Avoid contact with skin and eyes.
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

LFM A13 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-461)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Vassilev A., Ozer Z., Navara C., Mahajan S., & Uckun F.M. (1999). J. Biol. Chem. 274(3): 1646–1656.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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