| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide |
| Cas No. | |
| Form | Yellow solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO (10 mg/ml) or ethanol (0.3 mg/ml) |
| Source | Synthetic |
| Storage |
LFM A13 is a selective inhibitor of Bruton's tyrosine kinase (BTK), a key regulator of B-cell receptor signaling and innate immune responses. In neurodegenerative disease research, BTK has emerged as a target for modulating microglial activation and neuroinflammation. LFM A13 is used to explore the role of BTK in central nervous system immune responses and its potential as a therapeutic target in diseases such as multiple sclerosis and Alzheimer's disease.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
LFM A13 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-461)
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- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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