Nitrendipine

SKU:BHB11900109
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Nitrendipine is a research-grade small-molecule inhibitor of L-type Ca channel supporting Neuroscience and Ion Channels research. Supplied as a yellow crystalline solid with >98% purity (CAS 39562-70-4, MW 360.37) soluble in DMSO; store at -20°C. For research use only.
Cas No. 39562-70-4
Molecular Formula C18H20N2O6
Purity >98% (TLC)
Application Notes L-type Ca channel blocker
Options selector
Catalog no. Size
SIH-320-50MG 50 mg
SIH-320-250MG 250 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 250 mg, 50 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-320
Activity
  • Inhibitor
Alternative Names Ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate
Cas No. 39562-70-4
Form Yellow Crystalline Solid
Molecular Weight 360.37
Product Type
  • Biochemicals
  • Small Molecules
Purity >98% (TLC)
Shipping Shipped Ambient
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C
Solubility Soluble in DMSO (20mg/mL); or ethanol (10mg/mL)
Source Synthetic
Storage -20ºC

Nitrendipine is a dihydropyridine calcium channel blocker that targets L-type calcium channels in smooth muscle and neurons. By reducing calcium influx, it may help mitigate excitotoxicity—a key factor in neurodegeneration. Its neuroprotective potential is being explored in models of stroke and neurodegenerative diseases where calcium overload contributes to cell death.

Classification: Caution: Substance not fully tested yet.

Safety Phrases:

  • S22 - Do not breathe dust
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
  • S24/25- Avoid contact with shin and eyes

Risk Phrases:

R62 - Possible risk of impaired fertility

Hazard Phrases:

H312-H332

Precautionary Phrases:

P280

Nitrendipine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-320)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Peterson B.Z., Tanada T.N., Catterall W.A. (1996) J Biol Chem. 271: 5293-5296.

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