| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (S)-2,6-diamino-N-{[1'-(1''-oxotridecyl)-2'-piperidinyl]methyl}hexanamide . 2HCl |
| Cas No. | |
| Form | White to off-white solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in water, DMSO or methanol |
| Source | Synthetic |
| Storage |
NPC 15437 is a selective inhibitor of protein kinase C (PKC), acting through interaction with the regulatory domain at residues 12–42. In neuroscience, PKC signaling is involved in synaptic plasticity, memory formation, and neuroinflammation. NPC 15437 is used to study the role of PKC in neuronal signaling and to explore its contribution to neurodegenerative processes. By modulating PKC activity, NPC 15437 helps elucidate the molecular mechanisms underlying synaptic dysfunction and neurodegeneration in diseases such as Alzheimer’s and multiple sclerosis.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
NPC 15437 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-464)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Sullivan J.P., Connor J.R., Tiffany C., Shearer B.G., & Burch R.M. (1991) FEBS Letters. 285(1): 120–123.
