| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol; AK34095 |
| Cas No. | |
| Form | Off-white powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (40 mg/ml) |
| Source | Synthetic |
| Storage |
P7C3 is a neuroprotective compound that promotes neuronal survival by preventing apoptosis of newborn neurons. It has demonstrated efficacy in preserving cognitive function in aged animals and in models of neurodegenerative diseases such as ALS, Parkinson’s disease, and Down syndrome. P7C3 acts by activating nicotinamide phosphoribosyltransferase (NAMPT), leading to increased intracellular NAD⁺ levels. Its ability to enhance neurogenesis and protect against neuronal loss makes it a promising candidate for therapeutic development in neurodegeneration.
Hazard Statements:
- H301 (100%): Toxic if swallowed
- H318 (100%): Causes serious eye damage
Precautionary Statements:
P264, P270, P280, P301+P310, P305+P351+P338, P310, P321, P330, P405, and P501
P7C3 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-571)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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2. T Tesla et al. Proc. Natl. Acad. Sci. USA 2012 109:17016
3. H De Jesus-Cortes et al. Proc. Natl. Acad. Sci. USA 2012 109:17010
4. SE Latchney et al. Neurosci. Lett. 2015 591:86
5. G Wang et al. Cell 2014 158:1324