| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | E.coli-derived human PARG recombinant protein (Position: D27-R854) was used as the immunogen for the PARG antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
PARG Antibody / Poly(ADP-ribose) glycohydrolase is an antibody targeting PARG. Host: Rabbit. Polyclonal. Format: Lyophilized. Applications: WB, ICC/IF, FACS, ELISA.
Key elements and design rationale
- Target: PARG.
- Immunogen: E.coli-derived human PARG recombinant protein (Position: D27-R854) was used as the immunogen for the PARG antibody..
- Species reactivity: Human.
- Localization: Nuclear, cytoplasmic.
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
PARG antibody detects Poly(ADP-ribose) glycohydrolase, encoded by the PARG gene on chromosome 10q11.23. PARG antibody is widely used in DNA damage response, chromatin remodeling, and cancer biology research. PARG is the main enzyme responsible for degrading poly(ADP-ribose) chains, which are synthesized by PARP family enzymes in response to DNA breaks and stress signals.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IF/ICC: subcellular localization imaging with proper background controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.