| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 3,3′,4,5′-Tetrahydroxy-transstilbene; 4-[(E)-2-(3,5-Dihydroxyphenyl)vinyl]-1,2-benzenediol |
| Cas No. | |
| Form | Light Pink Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in 10 mg/ml DMSO or 10 mg/ml Ethanol |
| Source | Synthetic |
| Storage |
Piceatannol, a naturally occurring analog of resveratrol, is gaining recognition in neuroscience for its neuroprotective potential. It inhibits nonreceptor tyrosine kinases Syk and Lyk (IC50 ~10 µM) and activates Sirt1, a sirtuin linked to cellular longevity and neuroprotection.
These dual actions suggest a role in modulating neuroinflammatory pathways and oxidative stress—key contributors to neurodegenerative diseases such as Alzheimer’s and Parkinson’s. While traditionally cited in cancer and immunology research, Piceatannol’s emerging relevance in neuronal health highlights its value in developing targeted therapies for cognitive decline and age-related neurodegeneration.
Classification: Caution- Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S24/25- Avoid contact with skin and eyes
Piceatannol (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-358)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Howitz K.T., et al. (2003) Nature 425: 191.
