| Field | Specification |
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| Host | |
| Immunogen | A synthesized peptide derived from human PSMB10 was used as the immunogen for the PSMB10 antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
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| Target | |
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Overview
PSMB10 Antibody / Proteasome subunit beta type-10 is a anti-PSMB10 Rabbit antibody Recombinant Rabbit Monoclonal clone 30P41 supplied in Liquid format. Recommended for workflows such as Western blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) with listed reactivity in Human.
Key elements and design rationale
- Target: PSMB10
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 30P41, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): WB, ICC, IF
Biological background
PSMB10 antibody is widely applied in immunology, cancer biology, and infection research. The immunoproteasome is induced by interferon gamma and is enriched in immune tissues such as lymph nodes and spleen. Detection of PSMB10 provides insight into immune activation, antigen presentation, and adaptive immune responses. By monitoring PSMB10 expression, researchers can explore how immunoproteasome activity contributes to pathogen clearance and tumor surveillance.
Western blot assays identify PSMB10 protein bands in interferon-stimulated cells, while immunohistochemistry maps expression in lymphoid tissues. Immunofluorescence highlights cytoplasmic distribution within proteasome complexes. These applications make PSMB10 antibody a valuable tool for studying immune regulation.
PSMB10 has clinical significance in autoimmune disease, cancer, and viral infection. Dysregulated immunoproteasome activity alters antigen presentation, contributing to autoimmunity and chronic inflammation. Elevated PSMB10 expression has been linked to tumor immune evasion and therapy resistance. By applying PSMB10 antibody, scientists can investigate how immunoproteasome function affects immunity and pathology.
PSMB10 antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Western blotting: compare relative abundance and activation-state changes across conditions.
- Immunofluorescence: visualize subcellular distribution and cell-to-cell heterogeneity.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
