SNU-601 cell

SKU:BHC11101442
Bulk Pricing
Overview
Click light‑blue chips for details

SNU-601 cell is a cell line derived from East Asian (Male). It is commonly used as an in vitro model for 1 research. Growth characteristics: Adherent, Epithelial. Supplied as cryopreserved cells with accompanying batch CoA and quality-control documentation.

Species Human
Disease model Gastric signet ring cell adenocarcinoma
Morphology Epithelial
Growth Properties Adherent
Tissue Stomach
Options selector
Catalog no. Size
305282 1 cryovial
Available Options

This cell line is available in the U.S. For non-profit users, please sign and submit the Non-Profit Supply Agreement to orders@biohippo.com before placing an order. For commercial users, please complete the CLEAR Form before ordering, as additional usage fees may apply based on the intended use. For further details, please contact orders@biohippo.com. Products ship after the required agreement is completed; typical delivery is 2–3 business days. Products are shipped frozen on dry ice in cryotubes. Each cryotube typically contains 3 × 10^6 cells for adherent lines or 5 × 10^6 cells for suspension lines (refer to the batch CoA for details).

Field Specification
Mfr No 305282
Species Human
The SNU-601 cell line is derived from a poorly differentiated human gastric carcinoma and is widely utilized in gastric cancer research. This cell line serves as an important model for investigating the molecular and cellular mechanisms underlying gastric adenocarcinoma, which is a prevalent and often aggressive form of stomach cancer. SNU-601 cells are valuable for studying the genetic and epigenetic alterations associated with gastric cancer, as well as for testing the efficacy of potential therapeutic agents. SNU-601 cells exhibit an epithelial morphology and express markers characteristic of gastric carcinoma, including cytokeratins and carcinoembryonic antigen (CEA). They harbor genetic alterations commonly found in gastric cancer, such as mutations in oncogenes and tumor suppressor genes like TP53. Researchers use SNU-601 cells to explore key signaling pathways involved in gastric cancer progression, such as the PI3K/Akt, Wnt/β-catenin, and MAPK pathways. These cells are also employed in high-throughput drug screening assays and preclinical testing of chemotherapeutic agents, targeted therapies, and combination treatments. Additionally, SNU-601 cells are utilized to study mechanisms of drug resistance and to develop strategies to overcome it. The relevance of the SNU-601 cell line in gastric cancer research underscores its importance in advancing our understanding of this malignancy and in developing more effective treatments for gastric cancer patients.

SKU:BHC11101442

Mutational profile: Mutation: KRAS, p.Gly12Asp (c.35G>A), heterozygous; Mutation: PIK3CA, p.Glu542Lys (c.1624G>A), heterozygous; Mutation: TP53, p.Arg273His (c.818G>A), homozygous

  • cultureMedium: RPMI 1640, w: 2.0 mM stable Glutamine, w: 2.0 g/L NaHCO3 (Cytion article number 820700a)
  • supplements: Supplement the medium with 10% FBS, 25 mM HEPES
  • dissociationReagent: Accutase
  • subculturing: Remove the old medium from the adherent cells and wash them with PBS that lacks calcium and magnesium. For T25 flasks, use 3-5 ml of PBS, and for T75 flasks, use 5-10 ml. Then, cover the cells completely with Accutase, using 1-2 ml for T25 flasks and 2.5 ml for T75 flasks. Let the cells incubate at room temperature for 8-10 minutes to detach them. After incubation, gently mix the cells with 10 ml of medium to resuspend them, then centrifuge at 300xg for 3 minutes. Discard the supernatant, resuspend the cells in fresh medium, and transfer them into new flasks that already contain fresh medium.
  • freezeMedium: As a cryopreservation medium, use complete growth medium (including FBS) + 10% DMSO for adequate post-thaw viability, or CM-1 (Cytion catalog number 800100), which includes optimized osmoprotectants and metabolic stabilizers to enhance recovery and reduce cryo-induced stress.
Matches this product
10% OFF
10% OFF CELL LINES-Limited-Time Offer
Ends Sep 30 CELL10
15%OFF
15% Off Cancer Antibodies
Ends Sep 30 ONCO15
$50 OFF
$50 Off All ELISA Kits
Limited time ELISA50
FREE SAMPLE
Free Sample – CellTrypase Recombinant Trypsin-Like Enzyme
Limited time offer – availa... FREESAMPLE
FREE SAMPLE
Free Sample – MycoFold™ Growth Factors
Limited time offer – availa... Request Free Sample

Get a Quote

Please use this form for bulk quantity requests or customized products.

Contact Information

Product Information

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today