| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; 4-methylbenzenesulfonic acid |
| Cas No. | |
| Form | Off white powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble inDMSO (200mg/ml) or ethanol (3mg/ml) |
| Source | Synthetic |
| Storage |
Sorafenib is a multi-kinase inhibitor that targets several receptor tyrosine kinases including VEGFR, PDGFR, and Raf kinases. While primarily developed as an anticancer agent, Sorafenib is increasingly used in neuroscience to study angiogenesis, neurovascular remodeling, and kinase signaling in the brain. Its ability to modulate VEGF and Raf pathways makes it relevant in models of neuroinflammation, glioblastoma, and blood-brain barrier dysfunction. Sorafenib is a valuable tool for investigating the intersection of vascular and neuronal signaling in neurodegenerative disease research.
Classification: Not a hazardous substance or mixture.
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Sorafenib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-476)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
