| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | A synthesized peptide derived from human Somatostatin 28 was used as the immunogen for the SST antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
SST Antibody / Somatostatin is a anti-SST Rabbit antibody Recombinant Rabbit Monoclonal clone 31S68 supplied in Liquid format. Recommended for workflows such as Immunohistochemistry (IHC) with listed reactivity in Human, Mouse, Rat.
Key elements and design rationale
- Target: SST
- Antibody details: Rabbit, Recombinant Rabbit Monoclonal, clone 31S68, isotype Rabbit IgG
- Format: Liquid
- Applications (as listed): IHC
Biological background
SST antibody is widely used in endocrinology, neuroscience, and cancer research. In the pituitary gland, somatostatin regulates growth hormone release. In the pancreas, it modulates insulin and glucagon secretion. In the gastrointestinal tract, it suppresses acid secretion and motility. By detecting somatostatin, researchers can evaluate how this peptide coordinates endocrine and paracrine regulation across multiple organ systems.
Immunohistochemistry maps somatostatin producing cells in pancreatic islets, hypothalamus, and gastrointestinal mucosa. Immunofluorescence reveals somatostatin localization in neurons and endocrine cells, while ELISA enables quantitative analysis in serum or tissue extracts. These techniques make SST antibody a versatile tool for endocrine and neurological studies.
Somatostatin has clinical relevance as both a diagnostic marker and therapeutic target. Elevated somatostatin expression is observed in neuroendocrine tumors, while synthetic analogs such as octreotide are used to treat acromegaly, carcinoid syndrome, and other hormone secreting tumors. By applying SST antibody, scientists can investigate peptide hormone regulation, tumor biology, and therapeutic strategies targeting somatostatin pathways.
SST antibody from
Research relevance and current trends
- Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
- Considering isoforms and post-translational regulation when interpreting protein-level changes.
- Comparing results across species and model systems with matched controls.
Common research applications
- Immunohistochemistry: map target signal in tissue context and compare regions/phenotypes.
Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.
Notes for experimental interpretation
- Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
- Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.
Antibody notes: Monoclonal antibodies provide a defined epitope recognition profile that can support consistent comparisons across experiments.
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
