| Field | Specification |
|---|---|
| Mfr No | |
| Clonality | |
| Host | |
| Immunogen | E.coli-derived human TOP1MT recombinant protein (Position: E18-F601) was used as the immunogen for the TOP1MT antibody. |
| Isotype | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage | |
| Target | |
| UniProt # |
Overview
TOP1MT Antibody / DNA topoisomerase 1 mitochondrial is an antibody targeting TOP1MT. Host: Rabbit. Polyclonal. Format: Lyophilized. Applications: WB, IHC, FACS, ELISA.
Key elements and design rationale
- Target: TOP1MT.
- Immunogen: E.coli-derived human TOP1MT recombinant protein (Position: E18-F601) was used as the immunogen for the TOP1MT antibody..
- Species reactivity: Human, Mouse.
- Localization: Cytoplasmic (Mitochondria).
- Conjugate: Unconjugated (no label listed).
Biological background (from provided description)
TOP1MT antibody detects DNA topoisomerase 1 mitochondrial, encoded by the TOP1MT gene. DNA topoisomerase 1 mitochondrial is an enzyme located in the mitochondrial matrix that relaxes supercoiled mitochondrial DNA, enabling replication, transcription, and repair.
Common research applications
- WB: relative abundance and band pattern assessment using appropriate controls.
- IHC: tissue distribution assessment; interpret with matched controls.
Notes for experimental interpretation
- Account for isoforms, paralogs, and post-translational modifications when interpreting signal.
- Support specificity with biological controls (e.g., KO/KD where available) and technical controls (e.g., secondary-only/isotype).
Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
