| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | Thrombomodulin;TM;Fetomodulin;CD antigen CD141 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | Synthesized peptide derived from human CD141 AA range: 50-150 |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® CD141 (ABT145) Mouse Monoclonal Antibody (WM1689) is a mouse monoclonal antibody from UcallM Biosciences Inc, raised against CD141. It has been validated for Immunohistochemistry, ELISA and reacts with Human, Mouse, Rat.
Validated Applications
| Target | CD141 |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | ABT145 |
| Isotype | IgG2b, Kappa |
| Conjugate | Unconjugated |
| Reactivity | Human, Mouse, Rat |
| Applications | Immunohistochemistry, ELISA |
| Purification | Affinity Purified |
| Specificity | The antibody can specifically recognize human CD141 protein. |
| Molecular Weight | Calculated: 62 kDa | Observed: 100 kDa |
| UniProt / Swiss-Prot | P07204 (Human) |
Recommended dilutions: IHC 1:50-200;ELISA 1:500-5000
Immunogen / Antigen
Synthesized peptide derived from human CD141 AA range: 50-150
Reactivity Notes
Confirmed cross-reactivity: Human, Mouse, Rat. Confirm suitability for untested species before use.
Scientific Background
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
Safety & Handling
This antibody is validated for Immunohistochemistry, ELISA. Recommended dilutions: IHC 1:50-200;ELISA 1:500-5000
Confirmed reactivity: Human, Mouse, Rat. Other species should be validated by the user.
Conjugate: Unconjugated.
Store as follows: -15°C to -25°C/1 year(Do not lower than -25°C)
Clone ABT145.
Customization & Add-ons: Can't find exactly what you need? Contact us for custom formats, conjugations, bulk quantities, or related products.
