| Field | Specification |
|---|---|
| Alternative Names | Kbu |
| Clonality | |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | polypeptide |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Pan-Butyryllysine Mouse mAb is a monoclonal antibody raised in Mouse that specifically recognizes Butyryllysine (Lysine butyrylation [Lys(K)]). It is designed for detection and analysis of the Lysine butyrylation [Lys(K)] post-translational modification across research applications.
Lysine butyrylation is a newly discovered reversible post-translational modification, which is structurally analogous to lysine acetylation and lysine propionylation and participates in the regulation of protein biological activity. By virtue of integrated proteomic strategies and biochemical analysis, lysine butyrylation has been extensively identified in prokaryotes and eukaryotes, occurring on a large number of substrates including histones and non-histone proteins. Multiple lysine residues of histones and key non-histone proteins such as p53 and p300/CBP can undergo butyrylation modification. Lysine butyrylation exerts essential regulatory functions in epigenetic modulation, mainly by affecting chromatin dynamics and plasticity, mediating DNA transcription regulation, and participating in the occurrence and development of tumorigenesis and other pathological processes.
Validated Applications
| Application | Western Blot, Immunofluorescence |
|---|---|
| Recommended Dilution | WB 1:500-1:2000, ICC/IF 1:100 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Purification | Butyryl-lysine agarose affinity chromatography |
| Molecular Weight | Calculated: Multiple | Observed: Multiple |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Human, Mouse, Rat. It targets the Lysine butyrylation [Lys(K)] modification and is suitable for Western Blot, Immunofluorescence.
Safety & Handling
Related Products
Explore other UcallM Biosciences post-translational modification antibodies available through BioHippo.
It is validated for Western Blot, Immunofluorescence. Recommended dilutions: WB 1:500-1:2000, ICC/IF 1:100.
Use WB 1:500-1:2000, ICC/IF 1:100. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Butyryllysine (Lysine butyrylation [Lys(K)]); reactivity: Human, Mouse, Rat.
The monoclonal antibody (Mouse host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
Research budgets are tight — we get it. That's why we've put together a fresh round of exclusive promotions designed to help you stock up on the reagents, kits, and consumables your lab depends on, without stretching your budget.
🔬 What's on offer right now:
10% Off Pre-Designed siRNA Sets
20% Off Transmembrane Proteins
50% Off Lab Consumables + Free Shipping
$99 Pipette Filler Promotion Package
BlasTaq 2X qPCR MasterMix - 50% OFF Limited Time Offer
DENARASE® Endonuclease — 10% Off One Order
