| Field | Specification |
|---|---|
| Alternative Names | CCe |
| Clonality | |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | polypeptide |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Pan-Carboxyethyl-Cysteine Rabbit pAb is a polyclonal antibody raised in Rabbit that specifically recognizes Carboxyethyl-Cysteine (Cysteine carboxyethylation [Cys(C)]). It is designed for detection and analysis of the Cysteine carboxyethylation [Cys(C)] post-translational modification across research applications.
Carboxyethyl-Cysteine (CEC) is a novel post-translational modification occurring on cysteine residues of proteins. This modification is formed by covalently attaching a carboxyethyl group to the thiol group (-SH) of cysteine, generating a stable thioether linkage. CEC modification is widely distributed on histones and various functional proteins, and has been reported to be involved in cellular oxidative stress, metabolic regulation, protein stability, and a variety of physiological and pathological processes, making it an important target in protein modification and disease research.
Validated Applications
| Application | Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry |
|---|---|
| Recommended Dilution | WB 1:1000, IHC-P 1:100-1:200, ICC/IF 1:100-1:200, FC 1:100-1:200 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Species Independent |
| Conjugate | Unconjugated |
| Purification | Protein A |
| Molecular Weight | Calculated: Multiple | Observed: Multiple |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Species Independent. It targets the Cysteine carboxyethylation [Cys(C)] modification and is suitable for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry.
Safety & Handling
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It is validated for Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry. Recommended dilutions: WB 1:1000, IHC-P 1:100-1:200, ICC/IF 1:100-1:200, FC 1:100-1:200.
Use WB 1:1000, IHC-P 1:100-1:200, ICC/IF 1:100-1:200, FC 1:100-1:200. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Carboxyethyl-Cysteine (Cysteine carboxyethylation [Cys(C)]); reactivity: Species Independent.
The polyclonal antibody (Rabbit host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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