| Field | Specification |
|---|---|
| Alternative Names | Ksu |
| Clonality | |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | polypeptide |
| Isotype | |
| Molecular Weight | |
| Product Type | |
| Reactivity | |
| Storage | |
| Target |
Product Overview
U-Blot® Pan-Succinyllysine Mouse mAb is a monoclonal antibody raised in Mouse that specifically recognizes Succinyllysine (Lysine succinylation [Lys(K)]). It is designed for detection and analysis of the Lysine succinylation [Lys(K)] post-translational modification across research applications.
Succinyllysine (abbreviated as Ksucc) is an acylation-type post-translational modification occurring on lysine residues of proteins. By covalently attaching a succinyl group to the side chain of lysine, this modification markedly alters the charge and physicochemical properties of amino acid residues. Ksucc is widely distributed on both histone and non-histone proteins, and is critically involved in chromatin remodeling, gene transcription, energy metabolism, and mitochondrial function. It plays important regulatory roles in various pathological processes including cancer, metabolic diseases, and inflammatory responses, serving as a key target in the crosstalk between metabolism and epigenetics.
Validated Applications
| Application | Western Blot |
|---|---|
| Recommended Dilution | WB 1:500-1:1000 |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Purification | Protein G and immunogen affinity purified |
| Molecular Weight | Calculated: Multiple | Observed: Multiple |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Human, Mouse, Rat. It targets the Lysine succinylation [Lys(K)] modification and is suitable for Western Blot.
Safety & Handling
Related Products
Explore other UcallM Biosciences post-translational modification antibodies available through BioHippo.
It is validated for Western Blot. Recommended dilutions: WB 1:500-1:1000.
Use WB 1:500-1:1000. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Succinyllysine (Lysine succinylation [Lys(K)]); reactivity: Human, Mouse, Rat.
The monoclonal antibody (Mouse host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
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