| Field | Specification |
|---|---|
| Target | |
| Antigen | |
| Alternative names | SYN1 |
| Gene ID | |
| Host | |
| Clone | |
| Clonality | |
| Isotype | |
| Reactivity | |
| Applications | |
| Immunogen | polypeptide |
| Conjugate | |
| Molecular weight | |
| Purification | |
| Cellular localization | |
| Formulation | |
| Storage | |
| Catalog no. (Mfr.) | |
| Main SKU |
Product Overview
U-Blot® Phospho-Synapsin-1 (Ser9) Rabbit mAb is a recombinant monoclonal antibody raised in Rabbit that specifically recognizes Phospho-Synapsin-1 (Ser9) (Phosphorylation [Ser9]). It is designed for detection and analysis of the Phosphorylation [Ser9] post-translational modification across research applications.
Synapsin-1 is a subfamily of synaptic proteins that consists of at least 5 related members: Synapsin Ia, Ib, IIa, IIb, and IIIa. They play a critical regulatory role in the release of neurotransmitters and are highly abundant in the nervous system. All synapsins possess a short N-terminal domain that is conserved across the members and can be phosphorylated by protein kinase A (PKA) or calcium/calmodulin-dependent kinase I (CaM kinase I).Phosphorylation of the Ser9 site within the N-terminal domain of synapsin prevents its binding to phospholipids, resulting in the separation of synapsin from synaptic vesicles. When neurons receive stimulation, phosphorylated Synapsin-1 undergoes dephosphorylation, allowing it to rebind with phospholipids and facilitate the release of synaptic vesicles. This process enables the release of neurotransmitters and the transmission of neural signals.
Validated Applications
| Application | Western Blot |
|---|---|
| Recommended Dilution | WB 1:1000 |
| Host | Rabbit |
| Clonality | Recombinant Monoclonal |
| Isotype | IgG |
| Reactivity | Mouse, Rat |
| Conjugate | Unconjugated |
| Purification | Protein A |
| Molecular Weight | Calculated: 74 kDa | Observed: 85 kDa |
Immunogen / Antigen
polypeptide
Reactivity Notes
This antibody shows reactivity with Mouse, Rat. It targets the Phosphorylation [Ser9] modification and is suitable for Western Blot.
Safety & Handling
Related Products
Explore other UcallM Biosciences post-translational modification antibodies available through BioHippo.
It is validated for Western Blot. Recommended dilutions: WB 1:1000.
Use WB 1:1000. Optimal dilution should be determined empirically for your sample and detection system.
This is a pan-modification antibody recognizing Phospho-Synapsin-1 (Ser9) (Phosphorylation [Ser9]); reactivity: Mouse, Rat.
The recombinant monoclonal antibody (Rabbit host) was raised against polypeptide.
This product is supplied unconjugated. Contact BioHippo for custom conjugation or format options.
Store at -20°C. Avoid repeated freeze-thaw cycles | Stable for 12 months from date of receipt / reconstitution.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
