| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide, hydrochloride |
| Cas No. | |
| Form | White powder |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (40 mg/ml); or water (50 mg/ml) |
| Source | Synthetic |
| Storage |
UNC-2170 HCl is a selective inhibitor of the sodium-hydrogen exchanger isoform 1 (NHE1), a membrane protein involved in pH regulation and ion homeostasis. In neuroscience, NHE1 activity has been linked to excitotoxicity, neuroinflammation, and blood-brain barrier disruption. UNC-2170 HCl is used to study the role of NHE1 in ischemic brain injury, traumatic brain injury, and neurodegenerative diseases. By modulating intracellular pH and ion flux, it offers insights into mechanisms of neuronal injury and potential neuroprotective strategies.
UNC-2170 HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-559)
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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