| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | (3S)-3-{[(Benzyloxy)carbonyl]amino}-5-[(2,6-dichlorobenzoyl)oxy]-4-oxopentanoic acid |
| Cas No. | |
| Form | White to off-white Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in methanol (50 mg/ml) or DMSO |
| Source | Synthetic |
| Storage |
Z-Asp-CH2-DCB is a cell-permeable, irreversible broad-spectrum caspase inhibitor. It is widely used in neuroscience research to block apoptosis in neuronal cells under stress conditions such as hypoxia or excitotoxicity. By inhibiting caspase-mediated cell death pathways, Z-Asp-CH2-DCB helps preserve neuronal viability in models of neurodegenerative diseases and ischemic injury. Its utility in dissecting apoptotic mechanisms makes it a valuable tool in neurobiology.
Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Z-Asp-CH2-DCB (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-206)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
