| Field | Specification |
|---|---|
| Alternative names | N-[5-(3-Dimethylaminobenzamido)-2-methylphenyl]-4-hydroxybenzamide |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C23H23N3O3 |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble in DMSO (200 mg/ml) |
| SMILES | |
| InChIKey | |
| Form | White to off-white solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
ZM 336372 is a potent, specific, and reversible inhibitor of the c-Raf protein kinase. It also inhibits SAPK2/p38 and is cell-permeable. In neurodegenerative disease research, ZM 336372 is used to investigate the role of Raf signaling in neuronal survival, apoptosis, and stress responses. Its ability to modulate MAPK pathways makes it a valuable compound for studying neuroprotective mechanisms and therapeutic targets in conditions such as stroke and neuroinflammation.
Classification: Acute toxicity, Oral (Category 5)
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
H303 May be harmful if swallowed.
ZM 336372 (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-488)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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