Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters
Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer
908 products
Image ProductProduct Type ApplicationPrice Status ACTION
Human KCD18-Strep full length protein-synthetic nanodisc
New
Target: KCD18
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCD20-Strep full length protein-synthetic nanodisc
New
Target: KCD20
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCD17-Strep full length protein-synthetic nanodisc
New
Target: KCD17
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCD14-Strep full length protein-synthetic nanodisc
New
Target: KCD14
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCNE4-Strep full length protein-synthetic nanodisc
New
Target: KCNE4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCIP4-Strep full length protein-synthetic nanodisc
New
Target: KCIP4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCMB2-Strep full length protein-synthetic nanodisc
New
Target: KCMB2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCMB4-Strep full length protein-synthetic nanodisc
New
Target: KCMB4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCTD5-Strep full length protein-synthetic nanodisc
New
Target: KCTD5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human KCNE5-Strep full length protein-synthetic nanodisc
New
Target: KCNE5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human KCIP2-Strep full length protein-synthetic nanodisc
New
Target: KCIP2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCNE3-Strep full length protein-synthetic nanodisc
New
Target: KCNE3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCAB2-Strep full length protein-synthetic nanodisc
New
Target: KCAB2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human MRP4-Strep full length protein-synthetic nanodisc
New
Target: MRP4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human KCIP1-Strep full length protein-synthetic nanodisc
New
Target: KCIP1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human KCMB3-Strep full length protein-synthetic nanodisc
New
Target: KCMB3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human KCAB1-Strep full length protein-synthetic nanodisc
New
Target: KCAB1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human KCAB3-Strep full length protein-synthetic nanodisc
New
Target: KCAB3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human KCNE1-Strep full length protein-synthetic nanodisc
New
Target: KCNE1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human KCMB1-Strep full length protein-synthetic nanodisc
New
Target: KCMB1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human ICLN-Strep full length protein-synthetic nanodisc
New
Target: ICLN
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human KCNH2-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: KCNH2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human HCRTR2-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: HCRTR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human MC1R-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: MC1R
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human LPAR5-Strep full length protein-synthetic nanodisc
New
Target: LPAR5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MCHR2-Strep full length protein-synthetic nanodisc
New
Target: MCHR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MTR1L-Strep full length protein-synthetic nanodisc
New
Target: MTR1L
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human MTR1A-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: MTR1A
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MTLR-Strep full length protein-synthetic nanodisc
New
Target: MTLR
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MRGX3-Strep full length protein-synthetic nanodisc
New
Target: MRGX3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human LPAR1-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: LPAR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MTR1B-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: MTR1B
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MAS-Strep full length protein-synthetic nanodisc
New
Target: MAS
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MRGRE-Strep full length protein-synthetic nanodisc
New
Target: MRGRE
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human LPAR6-Strep full length protein-synthetic nanodisc
New
Target: LPAR6
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human MRGRD-Strep full length protein-synthetic nanodisc
New
Target: MRGRD
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

ConsiderationNanodiscDetergent micelleVLP
Lipid environmentNative lipid bilayer discDetergent shell (lipids removed)Native membrane on a capsid
Native function preservedHighVariable — often reduced for GPCRsHigh (keeps oligomeric state)
Best structural methodSingle-particle cryo-EMX-ray crystallography / LCPNot for high-resolution structure
Display / valencyMonomeric, defined stoichiometryMonomericMultivalent — many copies per particle
Typical particle~9–13 nm discProtein–detergent micelle~100 nm engineered capsid
Best forFunction + cryo-EM, SPR / BLI bindingBroad selection, high-res X-ray, costImmunization, antibody discovery, vaccines
Watch-outsDisc size caps very large complexesMay alter GPCR conformation / stabilityLess suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).

Recommended nanodisc products

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