Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters
Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer
908 products
Image ProductProduct Type ApplicationPrice Status ACTION
Human CRHR1-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: CRHR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CML2-Strep full length protein-synthetic nanodisc
New
Target: CML2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CELR1-Strep full length protein-synthetic nanodisc
New
Target: CELR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CRFR2-Strep full length protein-synthetic nanodisc
New
Target: CRFR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CLTR1-Strep full length protein-synthetic nanodisc
New
Target: CLTR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CLTR2-Strep full length protein-synthetic nanodisc
New
Target: CLTR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CELR3-Strep full length protein-synthetic nanodisc
New
Target: CELR3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CELR2-Strep full length protein-synthetic nanodisc
New
Target: CELR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CHRM3-Strep full length protein-synthetic nanodisc
New
Target: CHRM3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CMKLR1-Strep full length protein-synthetic nanodisc
New
Target: CMKLR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CX3CR1-Strep full length protein-synthetic nanodisc
New
Target: CX3CR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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Human CLPTM1-Strep full length protein-synthetic nanodisc
New
Target: CLPTM1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CXCR5-Strep full length protein-synthetic nanodisc
New
Target: CXCR5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CHRM2-Strep full length protein-synthetic nanodisc
New
Target: CHRM2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CXCR1-Strep full length protein-synthetic nanodisc
New
Target: CXCR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CLDN4-Strep full length protein-synthetic nanodisc
New
Target: CLDN4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CD36-Strep full length protein-synthetic nanodisc
New
Target: CD36
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CLDN3-Strep full length protein-synthetic nanodisc
New
Target: CLDN3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CLDN9-Strep full length protein-synthetic nanodisc
New
Target: CLDN9
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CLDN2-Strep full length protein-synthetic nanodisc
New
Target: CLDN2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CLDN18.2-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: CLDN18.2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CXCR2-Strep full length protein-synthetic nanodisc
New
Target: CXCR2
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
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Human CD39-Strep full length protein-synthetic nanodisc
New
Target: CD39
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CXCR4-Strep full length protein-synthetic nanodisc
New
Target: CXCR4
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CD151-Strep full length protein-synthetic nanodisc
New
Target: CD151
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
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In Stock at Manufacturer
Human CMTM6-Strep full length protein-synthetic nanodisc
New
Target: CMTM6
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CLDN5-Strep full length protein-synthetic nanodisc
New
Target: CLDN5
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CXCR3-Strep full length protein-synthetic nanodisc
New
Target: CXCR3
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CD63-Strep full length protein-synthetic nanodisc
New
Target: CD63
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CD47-Strep full length protein-synthetic nanodisc
New
Target: CD47
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CD81-Strep full length protein-synthetic nanodisc
New
Target: CD81
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CD20-Strep full length protein-synthetic nanodisc
New
Target: CD20
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CD37-Strep full length protein-synthetic nanodisc
New
Target: CD37
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CLDN6-Strep full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: CLDN6
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $810.00
Regular price From $810.00
In Stock at Manufacturer
Human CGRPR-RAMP1 full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: CGRPR
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $900.00
Regular price From $900.00
In Stock at Manufacturer
Human CMKLR1 full length protein-synthetic nanodisc – Figure 1 of 1
New
Target: CMKLR1
Transmembrane Protein Functional Assay (In Vitro) ELISA
From $900.00
Regular price From $900.00
In Stock at Manufacturer

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

ConsiderationNanodiscDetergent micelleVLP
Lipid environmentNative lipid bilayer discDetergent shell (lipids removed)Native membrane on a capsid
Native function preservedHighVariable — often reduced for GPCRsHigh (keeps oligomeric state)
Best structural methodSingle-particle cryo-EMX-ray crystallography / LCPNot for high-resolution structure
Display / valencyMonomeric, defined stoichiometryMonomericMultivalent — many copies per particle
Typical particle~9–13 nm discProtein–detergent micelle~100 nm engineered capsid
Best forFunction + cryo-EM, SPR / BLI bindingBroad selection, high-res X-ray, costImmunization, antibody discovery, vaccines
Watch-outsDisc size caps very large complexesMay alter GPCR conformation / stabilityLess suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).

Recommended nanodisc products

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