Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters

Other formats: Detergent micelle · VLP

Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer

908 products

Product	Product Type	Application	Price	Status	ACTION
New Human FFAR1-Strep full length protein-synthetic nanodisc Target: FFAR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human EMP2-Strep full length protein-synthetic nanodisc Target: EMP2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human CXCR6-Strep full length protein-synthetic nanodisc Target: CXCR6	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human GLP1R-Strep full length protein-synthetic nanodisc Target: GLP1R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human FZD7-Strep full length protein-synthetic nanodisc Target: FZD7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human GLP2R-Strep full length protein-synthetic nanodisc Target: GLP2R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human F2RL3-Strep full length protein-synthetic nanodisc Target: F2RL3	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human GNRHR-Strep full length protein-synthetic nanodisc Target: GNRHR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human CXCR7-Strep full length protein-synthetic nanodisc Target: CXCR7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human GCGR-Strep full length protein-synthetic nanodisc Target: GCGR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human FZD10-Strep full length protein-synthetic nanodisc Target: FZD10	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ENTPD2-Strep full length protein-synthetic nanodisc Target: ENTPD2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human FSHR-Strep full length protein-synthetic nanodisc Target: FSHR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human F2RL1-Strep full length protein-synthetic nanodisc Target: F2RL1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human F2RL2 full length protein-synthetic nanodisc Target: F2RL2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human FFAR4 full length protein-synthetic nanodisc Target: FFAR4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human DRD2 full length protein-synthetic nanodisc Target: DRD2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human FZD4 full length protein-synthetic nanodisc Target: FZD4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human EMP2 full length protein-synthetic nanodisc Target: EMP2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human GIPR full length protein-synthetic nanodisc Target: GIPR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human FFAR1 full length protein-synthetic nanodisc Target: FFAR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CXCR7 full length protein-synthetic nanodisc Target: CXCR7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human GLP1R full length protein-synthetic nanodisc Target: GLP1R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human GLP2R full length protein-synthetic nanodisc Target: GLP2R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human F2RL3 full length protein-synthetic nanodisc Target: F2RL3	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human FZD7 full length protein-synthetic nanodisc Target: FZD7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human GNRHR full length protein-synthetic nanodisc Target: GNRHR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ENTPD2 full length protein-synthetic nanodisc Target: ENTPD2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human GCGR full length protein-synthetic nanodisc Target: GCGR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human FZD10 full length protein-synthetic nanodisc Target: FZD10	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human F2RL1 full length protein-synthetic nanodisc Target: F2RL1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human FSHR full length protein-synthetic nanodisc Target: FSHR	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CLDN18.2-Strep full length protein-PeptiNanodisc Target: CLDN18.2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CLDN6-Strep full length protein-PeptiNanodisc Target: CLDN6	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CLDN18.1-Strep full length protein-PeptiNanodisc Target: CLDN18.1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CNGB1-Strep full length protein-synthetic nanodisc Target: CNGB1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

Consideration	Nanodisc	Detergent micelle	VLP
Lipid environment	Native lipid bilayer disc	Detergent shell (lipids removed)	Native membrane on a capsid
Native function preserved	High	Variable — often reduced for GPCRs	High (keeps oligomeric state)
Best structural method	Single-particle cryo-EM	X-ray crystallography / LCP	Not for high-resolution structure
Display / valency	Monomeric, defined stoichiometry	Monomeric	Multivalent — many copies per particle
Typical particle	~9–13 nm disc	Protein–detergent micelle	~100 nm engineered capsid
Best for	Function + cryo-EM, SPR / BLI binding	Broad selection, high-res X-ray, cost	Immunization, antibody discovery, vaccines
Watch-outs	Disc size caps very large complexes	May alter GPCR conformation / stability	Less suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).