Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters

Other formats: Detergent micelle · VLP

Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer

908 products

Product	Product Type	Application	Price	Status	ACTION
New Human ADORA1-Strep full length protein-synthetic nanodisc Target: ADORA1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADRB1-Strep full length protein-synthetic nanodisc Target: ADRB1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT2A-Strep full length protein-synthetic nanodisc Target: 5HT2A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT7R-Strep full length protein-synthetic nanodisc Target: 5HT7R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT1A-Strep full length protein-synthetic nanodisc Target: 5HT1A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACM1-Strep full length protein-synthetic nanodisc Target: ACM1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT4R-Strep full length protein-synthetic nanodisc Target: 5HT4R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT1E-Strep full length protein-synthetic nanodisc Target: 5HT1E	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT1D-Strep full length protein-synthetic nanodisc Target: 5HT1D	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT1F-Strep full length protein-synthetic nanodisc Target: 5HT1F	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT1B-Strep full length protein-synthetic nanodisc Target: 5HT1B	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADGRE5-Strep full length protein-synthetic nanodisc Target: ADGRE5	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADGRD1-Strep full length protein-synthetic nanodisc Target: ADGRD1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADGRG2-Strep full length protein-synthetic nanodisc Target: ADGRG2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADGRG1-Strep full length protein-synthetic nanodisc Target: ADGRG1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADORA2B-Strep full length protein-synthetic nanodisc Target: ADORA2B	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADGRE1-Strep full length protein-synthetic nanodisc Target: ADGRE1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ADGRE2-Strep full length protein-synthetic nanodisc Target: ADGRE2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Biotinylated Human CD4 full length protein-synthetic nanodisc Target: CD4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $990.00 Regular price From $990.00	In Stock at Manufacturer	View
New Human ADORA2A-Strep full length protein-synthetic nanodisc Target: ADORA2A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Biotinylated Human CD19 full length protein-synthetic nanodisc Target: CD19	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $990.00 Regular price From $990.00	In Stock at Manufacturer	View
New Human 5HT7R full length protein-synthetic nanodisc Target: 5HT7R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ABCG1 full length protein-synthetic nanodisc Target: ABCG1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ABCG2 full length protein-synthetic nanodisc Target: ABCG2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADRA2A full length protein-synthetic nanodisc Target: ADRA2A	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADRB1 full length protein-synthetic nanodisc Target: ADRB1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Biotinylated Human NK2R full length protein-synthetic nanodisc Target: NK2R	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $990.00 Regular price From $990.00	In Stock at Manufacturer	View
New Human ACKR1 full length protein-synthetic nanodisc Target: ACKR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADGRD1 full length protein-synthetic nanodisc Target: ADGRD1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADGRG1 full length protein-synthetic nanodisc Target: ADGRG1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADGRE5 full length protein-synthetic nanodisc Target: ADGRE5	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADGRG2 full length protein-synthetic nanodisc Target: ADGRG2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADGRE2 full length protein-synthetic nanodisc Target: ADGRE2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Biotinylated Human CLDN2 full length protein-synthetic nanodisc Target: CLDN2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $990.00 Regular price From $990.00	In Stock at Manufacturer	View
New Human ADORA2B full length protein-synthetic nanodisc Target: ADORA2B	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human ADGRE1 full length protein-synthetic nanodisc Target: ADGRE1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

Consideration	Nanodisc	Detergent micelle	VLP
Lipid environment	Native lipid bilayer disc	Detergent shell (lipids removed)	Native membrane on a capsid
Native function preserved	High	Variable — often reduced for GPCRs	High (keeps oligomeric state)
Best structural method	Single-particle cryo-EM	X-ray crystallography / LCP	Not for high-resolution structure
Display / valency	Monomeric, defined stoichiometry	Monomeric	Multivalent — many copies per particle
Typical particle	~9–13 nm disc	Protein–detergent micelle	~100 nm engineered capsid
Best for	Function + cryo-EM, SPR / BLI binding	Broad selection, high-res X-ray, cost	Immunization, antibody discovery, vaccines
Watch-outs	Disc size caps very large complexes	May alter GPCR conformation / stability	Less suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).