Nanodisc Membrane Proteins

Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.

Membrane proteinsNative lipid bilayerCryo-EM readyGPCRs & transporters

Other formats: Detergent micelle · VLP

Nanodisc: a membrane scaffold protein nanodisc placing the target protein in a native lipid bilayer

908 products

Product	Product Type	Application	Price	Status	ACTION
New Human BDKRB2 full length protein-synthetic nanodisc Target: BDKRB2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR5 full length protein-synthetic nanodisc Target: CCR5	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR1 full length protein-synthetic nanodisc Target: CCR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR3 full length protein-synthetic nanodisc Target: CCR3	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR8 full length protein-synthetic nanodisc Target: CCR8	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human C5AR2 full length protein-synthetic nanodisc Target: C5AR2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR6 full length protein-synthetic nanodisc Target: CCR6	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human C5AR1 full length protein-synthetic nanodisc Target: C5AR1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR7 full length protein-synthetic nanodisc Target: CCR7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CD151 full length protein-synthetic nanodisc Target: CD151	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR9 full length protein-synthetic nanodisc Target: CCR9	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human beta2AR-GPR75-BRIL full length protein-synthetic nanodisc Target: GPR75	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human BRIL-GPR75 full length protein-synthetic nanodisc Target: GPR75	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR2 full length protein-synthetic nanodisc Target: CCR2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CCR4 full length protein-synthetic nanodisc Target: CCR4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Human CB1 full length protein-synthetic nanodisc Target: CB1	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $900.00 Regular price From $900.00	In Stock at Manufacturer	View
New Biotinylated Human CD19 full length protein-PeptiNanodisc Target: CD19	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $1,089.00 Regular price From $1,089.00	In Stock at Manufacturer	View
New Biotinylated Human CCR8 full length protein-PeptiNanodisc Target: CCR8	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $1,089.00 Regular price From $1,089.00	In Stock at Manufacturer	View
New Biotinylated Human CCR2 full length protein-PeptiNanodisc Target: CCR2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $1,089.00 Regular price From $1,089.00	In Stock at Manufacturer	View
New Human ACHG-Strep full length protein-synthetic nanodisc Target: ACHG	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHA2-Strep full length protein-synthetic nanodisc Target: ACHA2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHA9-Strep full length protein-synthetic nanodisc Target: ACHA9	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT3E-Strep full length protein-synthetic nanodisc Target: 5HT3E	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHA7-Strep full length protein-synthetic nanodisc Target: ACHA7	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHB3-Strep full length protein-synthetic nanodisc Target: ACHB3	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHB2-Strep full length protein-synthetic nanodisc Target: ACHB2	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACH10-Strep full length protein-synthetic nanodisc Target: ACH10	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHE-Strep full length protein-synthetic nanodisc Target: ACHE	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHA6-Strep full length protein-synthetic nanodisc Target: ACHA6	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHB-Strep full length protein-synthetic nanodisc Target: ACHB	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHD-Strep full length protein-synthetic nanodisc Target: ACHD	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHB4-Strep full length protein-synthetic nanodisc Target: ACHB4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT3C-Strep full length protein-synthetic nanodisc Target: 5HT3C	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human 5HT3B-Strep full length protein-synthetic nanodisc Target: 5HT3B	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHA4-Strep full length protein-synthetic nanodisc Target: ACHA4	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View
New Human ACHA3-Strep full length protein-synthetic nanodisc Target: ACHA3	Transmembrane Protein	Functional Assay (In Vitro) ELISA	From $810.00 Regular price From $810.00	In Stock at Manufacturer	View

About Nanodisc Membrane Proteins

Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.

Choosing a membrane-protein format: Nanodisc vs Detergent vs VLP

Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.

Consideration	Nanodisc	Detergent micelle	VLP
Lipid environment	Native lipid bilayer disc	Detergent shell (lipids removed)	Native membrane on a capsid
Native function preserved	High	Variable — often reduced for GPCRs	High (keeps oligomeric state)
Best structural method	Single-particle cryo-EM	X-ray crystallography / LCP	Not for high-resolution structure
Display / valency	Monomeric, defined stoichiometry	Monomeric	Multivalent — many copies per particle
Typical particle	~9–13 nm disc	Protein–detergent micelle	~100 nm engineered capsid
Best for	Function + cryo-EM, SPR / BLI binding	Broad selection, high-res X-ray, cost	Immunization, antibody discovery, vaccines
Watch-outs	Disc size caps very large complexes	May alter GPCR conformation / stability	Less suited to atomic-resolution structure

How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).