Ribosomal protein S6 kinase alpha-1|S6K-alpha-1|90 kDa ribosomal protein S6 kinase 1|p90-RSK 1|p90RSK1|p90S6K|MAP kinase-activated protein kinase 1a|MAPK-activated protein kinase 1a|MAPKAP kinase 1a|MAPKAPK-1a|Ribosomal S6 kinase 1|RSK-1|RPS6KA1|MAPKAPK1A|RSK1|S6K-α1|S6K α1|S6Kα1
The family of ribosomal S6 kinases (Rsks), designated Rsk-1 (or MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular serine/threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development.
Homo Sapiens (Human)
Synthetic peptide, corresponding to amino acids 320-372 of Human Rsk-1.
Human, Mouse, Rat
Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.Specificity: Rsk-1 (T353) polyclonal antibody detects endogenous levels of Rsk-1 protein.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.