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Compound Overview
ABBV-969 Payload (CAS 2857037-70-6) is a research-grade small molecule supplied by TargetMol.
Physical Properties
| CAS Number | 2857037-70-6 |
|---|---|
| Molecular Formula | C36H38BrN5O9 |
| Molecular Weight | 764.62 g/mol |
| SMILES | CC(C)1(O)C(=O)OCc2c1cc1-c3nc4cc5OCOc5cc4c(c3Cn1c2=O)C12CC(C1)(C2)NC(=O… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
Br-Val-Ala-NH2-bicyclo(1.1.1)pentane-7-MAD-MDCPT (Formula V) is a conjugate comprising a potent topoisomerase I inhibitor linked to an antibody agent conjugate (ADC) (1) through a specialized linker.
Target(s): Others, Drug-Linker Conjugates for ADC
Signaling pathway(s): Others, Antibody-drug Conjugate/ADC Related
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Due to the small pack, the powder may be highly dispersed during shipping due to static electricity and may adhere to the vial. Please centrifuge and add an appropriate solvent to fully dissolve the product and prepare the stock solution.
If you are using DMSO for preparation,sterilization is not recommended, as DMSO itself possesses strong sterilizing properties. The prepared solution is sterile. For further assurance, it can be left overnight at 4°C. The safest method is to filter through a specialized organic filter membrane. If water is used for preparation,sterilization can be achieved by filtering through a 0.22 μm filter membrane.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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