1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC

SKU:BHB21902297
Overview
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1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC (CAS 137254-39-8) is an inhibitor supplied as a liquid. Relevant to Cell Cycle/DNA Damage and Apoptosis research. Molecular formula C48H88NO8P, molecular weight 838.19 g/mol.
Purity 99.9%
CAS Number 137254-39-8
Molecular Weight 838.19 g/mol
Form Liquid
Storage -20°C as supplied
Options selector
Catalog no. Size
HY-157647-5MG 5 mg (500 μL x 11.93 mM in Chloroform)
HY-157647-10MG 10 mg (1 mL x 11.93 mM in Chloroform)
HY-157647-25MG 25 mg (2.5 mL x 11.93 mM in Chloroform)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 5 mg (500 μL x 11.93 mM in Chloroform), 10 mg (1 mL x 11.93 mM in Chloroform), 25 mg (2.5 mL x 11.93 mM in Chloroform)
  • Lead time: shown per option in the variant selector.
  • Storage: Solution, -20°C, 2 years.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: transfer to -20°C as soon as possible.
Field Specification
Alternative names PC(18:0/22:4)
CAS no. 137254-39-8
Applications
  • Functional Assay (In Vitro)
Source Endogenous metabolite
Molecular weight 838.19
Molecular formula C48H88NO8P
Purity 99.9%
SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Form Liquid
Storage Solution, -20°C, 2 years.
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-157647
Main SKU BHB21902297
Inhibitors

Compound Overview

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PC, also known as PC(18:0/22:4), is an inhibitor of cyclin-dependent kinases (CDKs). It induces apoptosis and inhibits the growth of various cancer cell lines[1]. An endogenous metabolite, it is supplied as a colorless to light yellow liquid (C48H88NO8P, MW 838.19) at 99.9% purity.

Physical & Chemical Properties

CAS Number 137254-39-8
Molecular Formula C48H88NO8P
Molecular Weight 838.19 g/mol
Purity 99.9%
Appearance Liquid
Color Colorless to light yellow
SMILES CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(O[C@H](COC(CCCCCCCCCCCCCCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Signaling Pathway Cell Cycle/DNA Damage; Apoptosis
Initial Source Endogenous metabolite
Storage Solution, -20°C, 2 years.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Bell, M. V., et al. Molecular Species Composition of the Major Diacyl Glycerophospholipids from Muscle, Liver, Retina and Brain of Cod (Gadus morhua).  Lipids, 26(8), 565–573.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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