| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | 10-Formyltetrahydrofolic acid |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
10-FTHF (CAS 2800-34-2) is a research-grade small molecule supplied by TargetMol.
Alternative names: 10-Formyltetrahydrofolic acid
Physical Properties
| CAS Number | 2800-34-2 |
|---|---|
| Molecular Formula | C20H23N7O7 |
| Molecular Weight | 473.44 g/mol |
| SMILES | O=C1C2=C(NCC(CN(C=O)C3=CC=C(C(N(CH)(CCC(O)=O)C(O)=O)=O)C=C3)N2)NC(N)=N… |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
10-FTHF is a donor of formyl groups in anabolism used as a substrate in formyltransferase reactions, which is important in purine biosynthesis.
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
For currently available products, batch-specific purity data (HPLC chromatogram, NMR spectrum, and Certificate of Analysis) is accessible via the DataSheet link on the product page. For future or custom synthesis products, purity determination is conducted upon availability and published on the product page. Contact BioHippo for batch-specific CoA requests or custom synthesis enquiries.
For normal mice, the concentration of DMSO should be kept below 10%. For nude mice, transgenic mice, or mice with weak tolerance, the concentration of DMSO should be kept below 2%. For inhibitors being used for the first time, it is recommended to perform a solvent-negative control experiment to confirm that the solvent has no nonspecific effects on the animals.
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- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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