| Field | Specification |
|---|---|
| Alternative names | 11-dehydro-2,3-dinor TXB2 |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C18H28O6 |
| Purity | |
| SMILES | |
| Form | Liquid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
11-dehydro-2,3-dinor Thromboxane B2, also known as 11-dehydro-2,3-dinor TXB2, is a metabolite of the inactive TXA2 metabolite TXB2. It is formed from TXB2 by cytosolic aldehyde dehydrogenase (ALDH) and β-oxidation. Levels of 11-dehydro-2,3-dinor TXB2 have been reported to increase 5.2-fold in a surgery-induced rat model of tendon overuse. It is supplied as a colorless to light yellow liquid (C18H28O6, MW 340.41) at 99.0% purity.
Physical & Chemical Properties
| CAS Number | 79250-60-5 |
|---|---|
| Molecular Formula | C18H28O6 |
| Molecular Weight | 340.41 g/mol |
| Purity | 99.0% |
| Appearance | Liquid |
| Color | Colorless to light yellow |
| SMILES | O[C@@H]1[C@@H]([C@H](OC(C1)=O)/C=C/[C@@H](CCCCC)O)C/C=C\CC(O)=O |
| Signaling Pathway | Metabolic Enzyme/Protease |
| Storage | Solution, -20°C, 2 years. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
[1]. Roberts, et al. Metabolism of thromboxane B2 in Man. Identification of the major urinary metabolite. J. Biol. Chem. 256(16), 8384-8393 (1981).
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
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