| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C41H81NO4 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
18:0 DAP is a cationic or ionizable lipid with no unsaturated bonds in its hydrocarbon chain. Its mRNA encapsulation efficiency is 0%, and it cannot form functional lipid nanoparticles suitable for mRNA delivery[1]. It is supplied as a white to off-white solid (C41H81NO4, MW 652.09) at 99.99% purity.
Physical & Chemical Properties
| CAS Number | 121315-93-3 |
|---|---|
| Molecular Formula | C41H81NO4 |
| Molecular Weight | 652.09 g/mol |
| Purity | 99.99% |
| Appearance | Solid |
| Color | White to off-white |
| SMILES | CN(CC(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)C |
| Storage | Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
18:0 DAP (50 molar ratio; immediately after preparation) does not form functional LNPs with mRNA, as indicated by 0% encapsulation efficiency, large hydrodynamic size, and high PDI[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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