2,3-Dinor-8-iso prostaglandin F 2α

SKU:BHB21903353
Overview
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2,3-Dinor-8-iso prostaglandin F 2α (CAS 221664-05-7) is a drug metabolite. Relevant to Metabolic Enzyme/Protease research. Molecular formula C18H30O5, molecular weight 326.43 g/mol. Also known as 2,3-Dinor-8-isoPGF2α.
CAS Number 221664-05-7
Molecular Weight 326.43 g/mol
Storage See Certificate of Analysis
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Catalog no. Size
HY-W353470-25UG 25 μg
HY-W353470-50UG 50 μg
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  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
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Field Specification
Alternative names 2,3-Dinor-8-isoPGF2α
CAS no. 221664-05-7
Applications
  • Functional Assay (In Vitro)
Molecular weight 326.43
Molecular formula C18H30O5
SMILES OC(C/C=C\C[C@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-W353470
Main SKU BHB21903353
Drug Metabolites & Impurities

Compound Overview

2,3-Dinor-8-iso prostaglandin F 2α, also known as 2,3-Dinor-8-isoPGF2α, is the major β-oxidation metabolite of 8-iso-prostaglandin F₂α. It serves as a biomarker for evaluating the in vivo production of 8-iso-prostaglandin F₂α and the level of lipid peroxidation, and it can be used in the study of oxidative stress-related diseases such as arteriosclerosis and diabetes[1][2][3]. It has the molecular formula C18H30O5 and a molecular weight of 326.43 g/mol.

Physical & Chemical Properties

CAS Number 221664-05-7
Molecular Formula C18H30O5
Molecular Weight 326.43 g/mol
SMILES OC(C/C=C\C[C@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O
Signaling Pathway Metabolic Enzyme/Protease
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Liang Y, et al. Quantification of 8-iso-prostaglandin-F(2alpha) and 2,3-dinor-8-iso-prostaglandin-F(2alpha) in human urine using liquid chromatography-tandem mass spectrometry. Free Radic Biol Med. 2003 Feb 15;34(4):409-18.

[2]. Chiabrando C, et al. Identification and measurement of endogenous beta-oxidation metabolites of 8-epi-Prostaglandin F2alpha. J Biol Chem. 1999 Jan 15;274(3):1313-9.

[3]. Roberts LJ 2nd, et al. Identification of the major urinary metabolite of the F2-isoprostane 8-iso-prostaglandin F2alpha in humans. J Biol Chem. 1996 Aug 23;271(34):20617-20.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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