2-Aminotetralin

SKU:BHB21903267
Overview
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2-Aminotetralin (CAS 2954-50-9) is an agonist supplied as a solid. Reported to act on 5-HT 1A Receptor, 5-HT 1B Receptor, 5-HT 1D Receptor. Relevant to Neuronal Signaling research. Molecular formula C10H13N, molecular weight 147.22 g/mol.
CAS Number 2954-50-9
Molecular Weight 147.22 g/mol
Form Solid
Target 5-HT 1A Receptor +2 more
Storage Powder -20°C; in solvent -80°C
Options selector
Catalog no. Size
HY-W022362-50MG 50 mg
HY-W022362-100MG 100 mg
HY-W022362-500MG 500 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 50 mg, 100 mg, 500 mg
  • Lead time: made to order; typically ships within 2–3 weeks.
  • Storage: Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: transfer to -20°C as soon as possible.
Field Specification
Target 5-HT 1A Receptor, 5-HT 1B Receptor, 5-HT 1D Receptor
CAS no. 2954-50-9
Applications
  • Functional Assay (In Vitro)
Molecular weight 147.22
Molecular formula C10H13N
SMILES NC1CC2=C(C=CC=C2)CC1
Form Solid
Storage Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month.
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-W022362
Main SKU BHB21903267
Agonists

Compound Overview

2-Aminotetralin is a potent, selective serotonin 5-HT1 agonist. It exhibits high affinity (Ki ≤25 nM) and at least 50-fold stereoselective preference at the 5-HT1A, 5-HT1B and 5-HT1D receptors[1]. It is supplied as a solid (C10H13N, MW 147.22).

Physical & Chemical Properties

CAS Number 2954-50-9
Molecular Formula C10H13N
Molecular Weight 147.22 g/mol
Appearance Solid
SMILES NC1CC2=C(C=CC=C2)CC1
Target 5-HT 1A Receptor, 5-HT 1B Receptor, 5-HT 1D Receptor
Signaling Pathway Neuronal Signaling
Storage Powder: -20°C, 3 years. In solvent: -80°C, 6 months; -20°C, 1 month.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. McGlynn RP, et al. Development of 2-Aminotetralin-Type Serotonin 5-HT1 Agonists: Molecular Determinants for Selective Binding and Signaling at 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT1F Receptors. ACS Chem Neurosci. 2024 Jan 17;15(2):357-370.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

Q.How long does this take to ship?
A.This item is produced on request and typically ships within 2–3 weeks.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
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