| Field | Specification |
|---|---|
| Alternative names | 2'-Fluoro dATP sodium |
| Applications | |
| Molecular weight | |
| Molecular formula | C10H11FN5Na4O12P3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium, also known as 2'-Fluoro dATP sodium, is a fluorinated derivative of ATP. It acts as both a substrate and an inhibitor of E. coli DNA-dependent RNA polymerase, with a Ki of 200 μM[1]. It has the molecular formula C10H11FN5Na4O12P3 and a molecular weight of 597.10 g/mol.
Physical & Chemical Properties
| Molecular Formula | C10H11FN5Na4O12P3 |
|---|---|
| Molecular Weight | 597.10 g/mol |
| SMILES | NC1=C(N=CN2[C@H]3[C@H](F)[C@H](O)[C@@H](COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)O3)C2=NC=N1 |
| Signaling Pathway | Cell Cycle/DNA Damage |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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