2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium

SKU:BHB21900999
Overview
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2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium is a bioactive small molecule. Relevant to Cell Cycle/DNA Damage research. Molecular formula C10H11FLi4N5O12P3, molecular weight 532.90 g/mol. Also known as AfTP tetralithium, 2′-Fluoro-2′-deoxy-ATP (tetralithium).
Molecular Weight 532.90 g/mol
Storage See Certificate of Analysis
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Catalog no. Size
HY-136649-100UL 100 μL
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 100 μL
  • Lead time: shown per option in the variant selector.
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: store as stated on the Certificate of Analysis; contact us if you need the condition before ordering.
Field Specification
Alternative names AfTP tetralithium, 2′-Fluoro-2′-deoxy-ATP (tetralithium)
Applications
  • Functional Assay (In Vitro)
Molecular weight 532.90
Molecular formula C10H11FLi4N5O12P3
SMILES F[C@@H]([C@@H]1N2C3=C(C(N)=NC=N3)N=C2)[C@H](O)[C@H](O1)COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O
Storage Refer to Certificate of Analysis (CoA) for storage conditions
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-136649
Main SKU BHB21900999
Bioactive Small Molecules

Compound Overview

2'-Deoxy-2'-fluoroadenosine 5'-triphosphate tetralithium, also known as AfTP tetralithium or 2'-Fluoro-2'-deoxy-ATP (tetralithium), is an ATP analog that exerts a strong but mixed-type inhibition of poly(AU) synthesis. It has the molecular formula C10H11FLi4N5O12P3 and a molecular weight of 532.90 g/mol.

Physical & Chemical Properties

Molecular Formula C10H11FLi4N5O12P3
Molecular Weight 532.90 g/mol
SMILES F[C@@H]([C@@H]1N2C3=C(C(N)=NC=N3)N=C2)[C@H](O)[C@H](O1)COP(OP(OP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O
Signaling Pathway Cell Cycle/DNA Damage
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Kasuya T, et al. Highly accurate synthesis of the fully 2'-fluoro-modified oligonucleotide by Therminator DNA polymerases. Bioorg Med Chem Lett. 2014 May 1; 24(9): 2134-6.

[2]. Ishihama A, Enami M, Nishijima Y, Fukui T, Ohtsuka E, Ikehara M. 2'-Deoxy-2'-azidoadenosine triphosphate and 2'-deoxy-2'-fluoroadenosine triphosphate as substrates and inhibitors for Escherichia coli DNA-dependent RNA polymerase. J Biochem. 1980;87(3):825-830.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.

Q.Why is there no price listed?
A.Every size of this product is quoted on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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