| Field | Specification |
|---|---|
| Target | |
| Alternative names | 2'-Methyl GTP sodium |
| Applications | |
| Molecular weight | |
| Molecular formula | C11H14N5Na4O14P3 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
2'-O-Methylguanosine-5'-O-triphosphate sodium, also known as 2'-Methyl GTP sodium, is a methylated derivative of Guanosine 5'-triphosphate and an inhibitor of HCV NS5B RNA-dependent RNA polymerase. It acts as a nucleotide competitor of GTP and functions as a chain terminator that halts RNA synthesis. It can be used for HCV infection research[1]. It has the molecular formula C11H14N5Na4O14P3 and a molecular weight of 625.13 g/mol.
Physical & Chemical Properties
| Molecular Formula | C11H14N5Na4O14P3 |
|---|---|
| Molecular Weight | 625.13 g/mol |
| SMILES | O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](COP(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)[C@@H](O)[C@H]3OC |
| Target | RNA Polymerase |
| Signaling Pathway | Cell Cycle/DNA Damage |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
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