(2-pyridyldithio)-PEG1-hydrazine

SKU:BHB21900966
Overview
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(2-pyridyldithio)-PEG1-hydrazine (CAS 111625-28-6) is an ADC linker supplied as a liquid. Relevant to Antibody-Drug Conjugate/ADC Related research. Molecular formula C7H9NOS2, molecular weight 187.28 g/mol.
Purity 99.04%
CAS Number 111625-28-6
Molecular Weight 187.28 g/mol
Form Liquid
Storage 4°C as supplied; in solvent -80°C
Options selector
Catalog no. Size
HY-136135-100MG 100 mg
HY-136135-250MG 250 mg
HY-136135-1G 1 g
HY-136135-5G 5 g
HY-136135-25G 25 g
HY-136135-50G 50 g
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 100 mg, 250 mg, 1 g, 5 g, 25 g, 50 g
  • Lead time: varies by selected option.
  • Storage: 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen).
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: refrigerate at 4°C as soon as possible.
Field Specification
CAS no. 111625-28-6
Applications
  • Functional Assay (In Vitro)
Molecular weight 187.28
Molecular formula C7H9NOS2
Purity 99.04%
Activity
  • Cleavable Linker
  • Disulfide Cleavable Linker
SMILES OCCSSC1=NC=CC=C1
Form Liquid
Storage 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen).
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-136135
Main SKU BHB21900966
ADC Linkers & Payloads

Compound Overview

(2-pyridyldithio)-PEG1-hydrazine is a cleavable 1 unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. It is supplied as a colorless to light yellow liquid (C7H9NOS2, MW 187.28) at 99.04% purity.

Physical & Chemical Properties

CAS Number 111625-28-6
Molecular Formula C7H9NOS2
Molecular Weight 187.28 g/mol
Purity 99.04%
Appearance Liquid
Color Colorless to light yellow
Density 1.32 g/cm3
SMILES OCCSSC1=NC=CC=C1
Signaling Pathway Antibody-Drug Conjugate/ADC Related
Bioactivity Class Disulfide Cleavable Linker, Cleavable Linker
Storage 4°C, stored under nitrogen. In solvent: -80°C, 6 months; -20°C, 1 month (stored under nitrogen).
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

Q.Why is there no price on some sizes?
A.Availability and lead time for those sizes are confirmed on inquiry. Send us the size you need and we will come back with price and lead time.
Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

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