4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione

SKU:BHB21903311
Overview
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4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione (CAS 5426-09-5) is a nucleoside/nucleotide analog supplied as a solid. Relevant to Cell Cycle/DNA Damage research. Molecular formula C8H6O4, molecular weight 166.13 g/mol.
Purity 97.0%
CAS Number 5426-09-5
Molecular Weight 166.13 g/mol
Form Solid
Storage -20°C as supplied; in solvent -80°C
Options selector
Catalog no. Size
HY-W102981-1G 1 g
HY-W102981-5G 5 g
HY-W102981-10G 10 g
HY-W102981-25G 25 g
HY-W102981-50G 50 g
HY-W102981-100G 100 g
HY-W102981-1MLX10MM 1 mL x 10 mM (in DMSO)
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size: 1 g, 5 g, 10 g, 25 g, 50 g, 100 g, 1 mL x 10 mM (in DMSO)
  • Lead time: shown per option in the variant selector.
  • Storage: -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
  • Shipping: Room temperature in continental US; may vary elsewhere.
  • Upon receipt: transfer to -20°C as soon as possible.
Field Specification
Alternative names 7-Oxanorborna-2-ene-5,6-dicarboxylic anhydride
CAS no. 5426-09-5
Applications
  • Functional Assay (In Vitro)
Molecular weight 166.13
Molecular formula C8H6O4
Purity 97.0%
SMILES C1=CC2C3C(C1O2)C(=O)OC3=O
Form Solid
Storage -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
Shipping Room temperature in continental US; may vary elsewhere.
Catalog no. (Mfr.) HY-W102981
Main SKU BHB21903311
Nucleoside & Nucleotide Analogs

Compound Overview

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione, also known as 7-Oxanorborna-2-ene-5,6-dicarboxylic anhydride, is classified by the manufacturer as a purine nucleoside analog. Analogs of this class show broad antitumor activity against indolent lymphoid malignancies, acting through inhibition of DNA synthesis and induction of apoptosis, among other mechanisms[1]. It is supplied as a white to off-white solid (C8H6O4, MW 166.13) at 97.0% purity.

Physical & Chemical Properties

CAS Number 5426-09-5
Molecular Formula C8H6O4
Molecular Weight 166.13 g/mol
Purity 97.0%
Appearance Solid
Color White to off-white
SMILES C1=CC2C3C(C1O2)C(=O)OC3=O
Signaling Pathway Cell Cycle/DNA Damage
Solubility In Vitro: DMSO: ≥ 100 mg/mL (601.94 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) * "≥" means soluble, but saturation unknown.
Storage -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
Shipping Room temperature in continental US; may vary elsewhere.

Literature Cited

Sources cited in this description. Peer-reviewed publications that used this product are listed under References.

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Safety

For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.

In Vitro

SolventSolubilityNotes
DMSO≥ 100 mg/mL (601.94 mM)use freshly opened DMSO (absorbed moisture lowers solubility)

Aliquot the stock solution and store it at -80°C (up to 6 months) or -20°C (up to 1 month); sealed storage, away from moisture; avoid repeated freeze-thaw cycles.

Data provided by the manufacturer.

Q.Can this be used in humans or for diagnostics?
A.No. This product is supplied For Research Use Only. It is not for diagnostic or therapeutic procedures and not for human or veterinary use.

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