| Field | Specification |
|---|---|
| Alternative names | 4,4-MBP |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C29H44O2 |
| Purity | |
| SMILES | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
4,4'-Methylenebis(2,6-di-tert-butylphenol), also known as 4,4-MBP, is a bisphenol compound that inhibits sarco/endoplasmic reticulum calcium ATPase (SERCA) with an IC50 of 17 μM, and it can be applied in research on diseases related to calcium homeostasis[1]. It is supplied as a white to light yellow solid (C29H44O2, MW 424.66) at 99.83% purity.
Physical & Chemical Properties
| CAS Number | 118-82-1 |
|---|---|
| Molecular Formula | C29H44O2 |
| Molecular Weight | 424.66 g/mol |
| Purity | 99.83% |
| Appearance | Solid |
| Color | White to light yellow |
| SMILES | CC(C)(C)C1=C(C(=CC(=C1)CC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C)C(C)(C)C)O |
| Signaling Pathway | Neuronal Signaling; Membrane Transporter/Ion Channel |
| Solubility | In Vitro: DMSO: 5 mg/mL (11.77 mM; Requires sonication and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) |
| Storage | RT, stored under nitrogen. In solvent: -80°C, 1 year; -20°C, 6 months. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
| Solvent | Solubility | Notes |
|---|---|---|
| DMSO | 5 mg/mL (11.77 mM) | requires sonication and warming and heat to 60°C; use freshly opened DMSO (absorbed moisture lowers solubility) |
Aliquot the stock solution and store it at -80°C (up to 1 year) or -20°C (up to 6 months); avoid repeated freeze-thaw cycles.
Data provided by the manufacturer.
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